Research History
National Pancreas Foundation Grant Recipients 2000-2010
Peter A. Banks, MD Brigham & Women’s Hospital, Boston, MA
Prognostic Factors in Interstitial Pancreatitis
Michael Bouvet, MD San Diego VA Health Care System, University of California, San Diego
Tumor- stroma interactions in pancreatic cancer: the contribution of type 1 collagen to growth progression and metastasis
Rolf A. Brekken, Ph.D. University of Texas Southwestern Medical Center
Anti-Angiogenic Strategies for the Therapy of Pancreatic Cancer
Alphonso Brown, MD, MS Clin Epi Harvard Medical School – Beth Israel Deaconess Medical Center, Boston, MA
The Role of Plasma Fatty Acid Analysis and Arterial Spin Labeled MRI Perfusion Imaging in the Diagnosis of Chronic Pancreatitis in Subjects with Positive Secretin Studies but Negative Pancreatic Conventional Imaging Studies.
William R. Brugge, MD Massachusetts General Hospital
Detection of Malignancy in Cystic and Intraductal Tumors of the Pancreas: A Long Term Study of the Natural History
Mark P. Callery, M.D. University of Massachusetts Medical School
Mechanisms of Chemoresistance in Human Pancreatic Cancer
John M. Carethers, M.D. Veterans Medical Research Foundation, San Diego
TGFbeta Family Pathway Disruption in Pancreatic Cancers
Sara Cervantes-Roldan, PhD University of California, San Francisco, CA
Role of Hedgehog Signaling in the Stroma During Pancreatic Adenocarcinoma Progression
Yan Chen, MD, PhD Indiana University School of Medicine
Studies of a Pancreatic Mouse Model with Disruption of TGF-beta Signaling
Chuhan Chung, MD, Yale University
Regulation of Pancreatic Fibrotic Responses by Pigment Epithelium-Derived Factor (PEDF)
Edna Cukierman, Ph.D. Institute for Cancer Research, Fox Chase Cancer Center
A Study of Desmoplasia Permissiveness in Tumor Progression of Patients with Pancreatic Cancer
Joseph J. Cullen, MD University of Iowa
Treatment of Pancreatic Cancer with 2-Deoxy-D-glucose (2DG)
Rajinder K. Dawra, PhD University of Minnesota, Minneapolis, MN
Lysosomal Permeability in Pathogenesis of Pancreatitis – A New Paradigm
Therese B. Deramaudt, Ph.D. University of Pennsylvania
Molecular Pathogenesis of Pancreatic Cancer
Saleem Desai, M.D. Brigham and Women’s Hospital
Investigation of the Role of Pax 6 in the Pancreas (2 year grant)
Marina Pasca Di Magliano, PhD University of California, San Francisco
The role of the Hedgehog signaling pathway in pancreatic cancer
Giamila Fantuzzi, PhD University of Illinois at Chicago, Chicago, IL
Interleukin-6 in Experimental Acute Pancreatitis
Steven D. Freedman, M.D., Ph.D. Harvard Medical School/BI Deaconess Hospital
The Effect of Repetitive Transcranial Magnetic Stimulation on Abdominal Pain in Patients with Chronic Pancreatitis. Do Cystic Fibrosis Gene Mutations Predispose Patients with Pancreas Divisum to Pancreatitis?
Felipe Fregni, MD, PhD Beth Israel Deaconess Medical School-Harvard Medical School, Boston, MA
The Effect of a 10-day treatment with Transcranial Magnetic Stimulation on Abdominal Pain in Patients with Locally Advanced and Advanced Pancreatic Cancer, a Randomized Phase II Study
Akihisa Fukuda, MD, PhD, University of California San Francisco
The Role of Stat3 Signaling in the Initiation of Pancreatic Ductal Adenocarcinoma
Timothy B. Gardner, MD Dartmouth-Hitchcock Medical Center, Lebanon, NH
A Pilot Study Evaluating the Feasibility of Performing Combined Endoscopic Ultrasound Morphologic Evaluation, Endoscopic Pancreatic Function Testing, and Dynamic EUS Ductal Evaluation after Human Secretin Stimulation in one Endoscopic Session for the Diagnosis of Exocrine Pancreas Disease
Bidyut Ghosh, PhD Johns Hopkins University, Baltimore, MD
MicroRNA and Pancreas Specific Transcription Factor Ptf1-p48 in Pancreas Development
Michael Goggins, M.D. Johns Hopkins University School of Medicine
Bringing Chips from Bench to Bedside: using proteomics to identify novel pancreatic cancer proteins
Christine A. Hrycyna, PhD. Purdue University Deparment of Chemistry
Ras Carbozylmethyltransferase as a Target for Pancreatic Cancer Drug Discovery (2 year grant)
Rosa F. Hwang, MD University of Texas-M.D. Anderson Cancer Center
The Effect of S100P on Tumor-Stromal Interactions in Pancreatic Cancer
Kamel Izeradjene, PhD Fred Hutchinson Cancer Research Center, Seattle, WA
Molecular Pathways Underlying Different Routes to Pancreatic Ductal Adenocarcinoma
Amarsanaa Jazag, MD, PhD Brigham & Women’s Hospital, Boston, MA
A Silencing Vector Triad (SVT) for the Therapy of Pancreatic Cancer
Andrew M. Lowy, MD University of Cincinnati
The Ron Receptor in Pancreatic Cancer
Raymond J. MacDonald, PhD University of Texas Southwestern Medical Center, Dallas, TX
New Insights into the Embryonic Development of the Acinar Pancreas
Ashim Malhotra, PhD, New York University School of Medicine
The Role of Dendritic Cells in Pancreatic Fibrosis and the Development of Pancreatic Neoplasia
Anirban Maitra, M.D. Johns Hopkins University School of Medicine
Designing a High-throughput Sequencing Microarray for Risk Assessment in Familial Pancreatic Cancer (2 year grant)
Gail Matters, PhD Penn State College of Medicine
Impeding Pancreatic Cancer Growth and Metastasis by targeted down-regulation of Gastrin and Cholecystokinin
Daniel Meruelo, Ph.D. New York University School of Medicine
A Potential New Therapy for Pancreatic Cancer
Veronique D. Morinville, MD University of Pittsburgh Medical Center
Hereditary Pancreatitis Amlodipine Trial (H-PAT)
Hidayatullah G. Munshi, MD Northwestern University, Chicago, IL
Desmoplastic Reaction and Pancreatic Cancer Progression
Barry D. Nelkin, PhD Johns Hopkins University, Baltimore, MD
Effect of CDK5 Inhibition on Metastasis and Chemosensitivity in Pancreatic Cancer
Brent A. Neuschwander-Tetri, MD Saint Louis University
Role of the angiotensin receptor type 2 (AT2) in regulating pancreatic stellate cell apoptosis during recovery from injury
Anna-Liisa Nieminen, PhD Case Western Reserve University
Redox Regulation of Hypoxic Apoptosis in Pancreatic Cancer
Lee F. Peng, MD, PhD Massachusetts General Hospital
Application of Chemical Biology to the Study of Pancreatic Development Biology (2 years)
Maximilian Reichert, MD University of Pennsylvania, Philadelphia, PA
The Molecular Regulation of Pancreatic Centroacinar Cells
Andrew Rhim, MD, University of Pennsylvania
Translational Studies of Circulating Pancreatic Epithelial Cells in Cancer Progression
Miklos Sahin-Toth, MD, PhD Boston University Medical Center
SPINK 1 mini genes to study intronic mutations
Isaac Samuel, M.D. University of Iowa Health Care
Pathogens of Gallstone-Induced Acute Pancreatitis
Maria Dolors Sans Gili, PhD University of Michigan, Ann Arbor, MI
Role of Pancreatic Digestive Enzyme Synthesis During the Development of Acute Pancreatitis
Norihiro Sato, MD, PhD Johns Hopkins University School of Medicine
Functional Effects of RELN Inactivation on Pancreatic Cancer Progression
James Scheiman, MD University of Michigan, Ann Arbor, MI
Neoplasia Detection in Pancreatic Mass Lesions using Tissue Optical Spectroscopy
Thomas D. Schmittgen, PhD Ohio State University
Antisense knockdown of microRNA for pancreatic cancer therapy
Vijay Singh, MD, University of Pittsburgh Medical Center
Role of Src in Antegrade Golgi Expansion and Autophagic Acinar Cell Death
Tyler Stevens, MD Cleveland Clinic Foundation
Validation of Endoscopic Ultrasound Criteria for the Diagnosis of Chronic Pancreatitis using Dual Secretin and Cholecystokinin-stimulated Pancreatic Function Testing as Reference Standard
David ER Sutherland, MD, PhD University of Minnesota, Minneapolis, MN
Prospective Study of Outcomes Following Pancreatectomy and Autologous Islet Transplantation for Treatment of Pancreatic Disease
Richard Szmola, MD, PhD Boston University, Boston, MA
Chymotrypsin C Secretion Defects in Chronic Pancreatitis
Michael B. Wallace, M.D., MPH Medical University of South Carolina
Proposal of Phase II trial of EUS guided celiac plexus neurolysis of pancreatic cancer pain
Andrew L. Warshaw, M.D. Harvard Medical School/Mass General Hospital
Role of matrix metalloproteinase for leukocyte trafficking and alveolar capillary leakage in pancreatitis-associated lung injury
Melanie Wescott, PhD University of Pennsylvania, Philadelphia, PA
The Role of PDX1 in Pancreatic Ductal Development and Cancer
Edward E. Whang, M.D. Brigham & Women’s Hospital
The Role of Ribosomal Proteins in Pancreatic Cancer (2 year grant)
Targeted Nanoparticles: A New Therapeutic Strategy for Pancreatic Cancer
Juergen K. Willmann, MD, PhD Stanford University, Stanford, CA
Development of a Novel Translatable Molecular Imaging Approach for Early Detection of Pancreatic Cancer
David Whitcomb, M.D., PhD University of Pittsburgh Medical Center/Office of Research
Genetic Linkage Study for Familial Pancreatic Cancer
Predictive Modeling of Variations in the Post-ERCP Inflammatory Response
Obesity and Adipokines in Determining the Severity of Acute Pancreatitis
Kai Xia, MD.,PhD. Brigham and Women’s Hospital
Role of Raf and Sre Kinases in Pancreatic Cancer Development
Xiulong Xu, PhD Rush Presbyterian St. Luke’s Medical Center
Heparanase gene expression and tumor metastases in pancreatic neoplasms (2 year grant)
