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Grant Title: Non-Tumorigenic Support Cells Fuel Pancreatic Cancer Metabolism

Grant Year: 2016

Recipient: Costas A. Lyssiotis, PhD
Assistant Professor
University of Michigan Medical School

“My group’s NPF supported research provided preliminary data that was used as the basis for an AACR Next Generation of Cancer Scientists award. It is a point of pride that my research group has been affiliated with the NPF. This research grant mechanism is of great value and should continue to be targeted toward young investigators.”


Publications stemmed from The NPF Research Grant:

Schofield HK, Zeller J, Espinoza C, del Vecchio A, Magnuson BR, Halbrook CJ, Fabo T, Daylan AEC, Kovalenko I, Lee H-J, Yan W, Feng Y, Karim SA, Kremer D, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galban S, Fearon ER, Pasca di Magliano M. Differential Roles of Mutant p53R270H in Cancer Development Versus Established Growth in Pancreatic Cancer. JCI Insight, in press.

Halbrook C, Pasca di Magliano M, Lyssiotis CA. Metabolic Support Networks of the Tumor Microenvironment. American Journal of Physiology: Gastrointestinal and Liver, under review.

Halbrook C, Lyssiotis CA. Employing Metabolism To Improve The Diagnosis And Treatment Of Pancreatic Cancer. Cancer Cell 2017;31:5–19.

Social Media Contact
Twitter: @LyssiotisLab