Clinical Trial Resource Center

Welcome to the National Pancreas Foundation Clinical Trials Resource Center, presented in partnership with CenterWatch, the leading publisher of information on clinical research for patients, their advocates and healthcare professionals. Please click on the links below to learn more about clinical research and about new medical therapies for treating pancreas disease and related indications.

About Clinical Research

This section provides background information about the clinical trials process and what to expect when you volunteer to participate in a clinical trial. Here, you’ll find answers to frequently asked questions about clinical trials and also suggestions for where to find more information.

Listing of Clinical Trials

TITLE: Chronic Pancreatitis Trial – Kangen Pharmaceuticals.  A Phase 2, randomized, DOUBLE-BLIND, PARALLEL‑GROUP dose-ranging STUDY TO EVALUATE THE Safety and efficacy OF Ni-03 compared to placebo in subjects with chronic pancreatitis.

A multicenter, randomized, double-blind, placebo controlled study of three doses of NI-03. The aim of the study is to evaluate if the study drug is effective in treating the acute symptoms of chronic pancreatitis when given for 4 weeks. The study is currently enrolling patients nationwide.

If you or someone you love is 18 years of age or older and diagnosed with Chronic Pancreatitis, you may qualify for a clinical trial. Please CLICK HERE to visit the TACTIC study website to answer a few simple questions about your Chronic Pancreatitis and locate a site neaestr you. Eligible participants will receive study related treatment at no charge, and will also receive compensation for their time and travel.


TITLE: ISIS 304801-CS7 The APPROACH Open Label Study Volanesorsen (ISIS 304801) An Open-Label Study of Volanesorsen Administered Subcutaneously to Patients With Familial Chylomicronemia Syndrome (FCS) (Phase III Clinical Trial for Familial Chylomicronemia Syndrome (FCS)

This is a multi-center, open-label study. All patients will receive volanesorsen 300 mg once per week for 52 weeks. Patients will have the option of continuing dosing for an additional 52 weeks until an expanded access program is approved and available in their country. For more information, please CLICK HERE.


TITLE: SpHincterotomy for Acute Recurrent Pancreatitis (SHARP)

This NIH-sponsored Randomized Clinical Trial is currently enrolling subjects to learn whether an Endoscopic Retrograde CholangioPancreatography (ERCP) with sphincterotomy is beneficial in patients with acute recurrent pancreatitis and pancreas divisum.

The purpose of this study is to determine if a ERCP with sphincterotomy reduces the risk of pancreatitis or the number of recurrent pancreatitis episodes in patients with pancreas divisum. ERCP with sphincterotomy is a procedure where doctors used a combination of x-rays and an endoscope (a long flexible lighted tube) to find the opening of the duct where fluid drains out of the pancreas. People who have been diagnosed with pancreas divisum, have had at least two episodes of pancreatitis, and are candidates for the ERCP with sphincterotomy procedure may be eligible to participate. Participants will be will be randomly assigned to either have the ERCP with sphincterotomy procedure, or to have a “sham” procedure. Participants will have follow up visits 30 days after the procedure, 6 months after the procedure, and continuing every 6 months until a maximum follow-up period of 48 months.

For more information:
*Information about the study and contact on sites is available here: https://clinicaltrials.gov/ct2/show/study/NCT03609944
Current recruiting sites are: 
Dartmouth: https://www.dartmouth-hitchcock.org/
Indiana: http://medicine.iupui.edu/ercp
MUSC: http://ddc.musc.edu/research/feature-study.html
Northwestern: https://www.nm.org/conditions-and-care-areas/digestive-health/pancreatobiliary-program
Ohio State University: https://wexnermedical.osu.edu/departments/internal-medicine/gastroenterology/research
University of Minnesota: https://www.mhealth.org/care/overarching-care/pancreas-and-biliary-adult
VMMC: https://www.virginiamason.org/Pancreatitis
University of Alabama at Birmingham: https://www.uab.edu/medicine/gastroenterology/

The following sites which have since started enrolling in the study (no links available at this time):
Health Sciences Centre, Winnipeg, Manitoba, Canada
Keck Hospital of USC, Los Angeles, CA
Methodist Dallas Medical Center, Dallas, TX
Saint Luke’s Hospital of Kansas City
University of Pittsburgh Medical Center
University of Virginia

*https://www.youtube.com/watch?v=-GIM9_zje0I

If you are interested participating, please call (843) 876-4261


Title: THE IMPACT STUDY

This research study is for adults with pain from chronic pancreatitis

Researchers at Mayo Clinic and Seattle Children’s Research Institute want to find out about the usefulness of an online pain self-management program for adults with pain from Chronic Pancreatitis.

This study might be a good fit for you if:
*You are 18 years old or older
*You have been diagnosed with chronic pancreatitis and experience pain
*Have access to a web-enabled device

Adults who participate in the research study will:
**Complete online questionnaires about their pain, mood and health at 3 time points over 6 months
**Be randomly assigned to use an online program for 8 weeks that may help you manage your pain from chronic pancreatitis or be assigned to a condition where you receive your usual care for pancreatitis

**Earn up to $120 in gift cards

For more information, please contact study staff at Seattle Children’s Research Institute 206- 884-6312. (If you don’t answer right away, please leave your name and number and they will call you back as soon as possible) Or email: palermolab@seattlechildrens.org

 


Please see below for more details on: 

 

Listing of Studies at the National Institutes of Health

This listing includes government-funded clinical research studies being conducted by the various National Institutes of Health

Email Notification Service

Register your email address to be notified when new pancreas disease trials are posted to the database.

FDA Drug Approvals

This is a comprehensive listing of drugs that have recently been approved by the Food and Drug Administration. The drugs are organized by therapeutic area.

Research Centers

This directory provides detailed profiles of hundreds of clinical research centers organized geographically by state, city and center name.

CenterWatch Research Headlines

Here you’ll find links to news articles and reports on recent advances in clinical research. This section is updated weekly and the information has been published in CenterWatch publications during the past weeks. There may not always be gastroenterology-related material included.

New Medical Therapies (NMT) Trial Results

NMT Weekly Trial Results database is provides easy access to information about the results of recently completed and ongoing clinical trials. It is based on published materials from conferences, journals and company reports. The trial results summaries typically include the name and phase of the drug, the company sponsoring the research, and information on how well the drug has performed.

Patient Bookstore

Contains a variety of reports, brochures and publications that patients and their advocates can use to learn more about the clinical trials industry and how to identify and volunteer for clinical trials.