Patient Resources

Understanding & Managing Pancreatic Pain

Pain is a common part of pancreatic disease, but you don’t have to simply “live with it.” Medications, procedures, everyday strategies, and emotional support can all help you feel better.

Talking With Your Doctor About Pain

Because pancreatic pain has different causes, treatment is personalized. How you describe your pain helps your care team understand and treat it. If your pain is persistent, getting worse, or interfering with daily life, talk with your healthcare team.

Keep a Pain Diary. Tracking your symptoms helps you spot patterns and gives your doctor a clearer picture. Consider noting:

  • Where the pain occurs and whether it spreads to your back or other areas
  • What it feels like: aching, sharp, burning, or cramping
  • When it happens and how long it lasts
  • How severe it is, on a 0–10 scale
  • What makes it better or worse, such as food, movement, stress, or medications
  • How it affects your life, including eating, sleeping, working, and exercising

Tip: Bring a complete list of your medications, including over-the-counter medicines and supplements, to every appointment.

Treatment Options

No single treatment works for everyone. Your plan will depend on the cause and severity of your pain and your overall health.

Medications

Your provider may recommend over-the-counter pain relievers, medications for nerve-related pain, or opioids for severe pain when other treatments aren’t enough. Take medications only as directed, and talk with your provider before changing or stopping a prescription.

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Procedures

When pain is related to problems with the pancreatic or bile ducts, a procedure may help.

‍Celiac plexus block: Medication is injected near a group of nerves that carry pain signals from the upper abdomen. This may provide temporary relief for some people.

‍ERCP: This procedure can treat certain pancreatic and bile duct problems, such as a blockage. For some people, a narrowed or blocked pancreatic duct can be drained or stented during ERCP. Because ERCP can cause pancreatitis, it is not routinely used to diagnose it.

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Surgery

For severe, debilitating pain that hasn’t improved with other treatments, surgery may be considered. The type of surgery depends on the underlying disease and anatomy.

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Understanding Opioids

If you have concerns about opioid use, talk openly with your care team. They can help balance pain relief with medication safety and watch for potential problems. Three terms are often confused, but they mean different things.

Tolerance

The body becomes used to a medication, so a higher dose may be needed for the same effect. Tolerance can happen with regular use and does not by itself mean addiction.

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Physical Dependence

The body has adapted to a medication. Stopping suddenly after regular use can cause withdrawal symptoms such as sweating, nausea, diarrhea, anxiety, restlessness, or irritability. This is a predictable response and is different from addiction.

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Addiction

A chronic condition marked by compulsive use, difficulty controlling use, and continued use despite harmful consequences. A person can take an opioid as prescribed and develop dependence without developing addiction.

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Complementary & Everyday Strategies

Some people find these approaches helpful alongside medical treatment:

  • Gentle movement, stretching, or walking
  • Yoga
  • Massage
  • Deep breathing, meditation, or relaxation
  • Acupuncture
  • Heat, such as a heating pad
  • Time with supportive friends and family
  • Activities that offer distraction or relaxation

Note: What works varies from person to person. Talk with your provider before starting a new therapy, especially if you take medications or have other health conditions.

Caring for the Whole Person

Living with ongoing pain can affect your sleep, mood, relationships, and overall well-being. Your care team may include a pain specialist, gastroenterologist, dietitian, physical therapist, psychologist, social worker, or other specialists who can help with different parts of living with pancreatic disease. You don’t have to manage pancreatic pain alone.

Since 1997, the National Pancreas Foundation has been the only nonprofit dedicated to all diseases of the pancreas — funding grassroots research, backing early-career researchers, and connecting patients to an unmatched network of physicians and scientists. We believe better outcomes are possible, and we're working to make them a reality.

Pain Self-Management Guide
The National Pancreas Foundation

The only nonprofit dedicated to all diseases of the pancreas — advancing research, education, and patient care.

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